The Effect of Preoperative Nutrition on Postoperative CRP and Albumin Levels in Patients Undergoing Laparoscopic Surgery: A Surgical Nursing Perspective

Abstract

PurposeThe purpose of this study was to investigate the effect of preoperative oral carbohydrate on postoperative serum C-reactive protein (CRP) and albumin levels in patients laparoscopic surgery. DesignThis is an experimental study with intervention and control groups. MethodsSixty-six patients who underwent elective laparoscopic cholecystectomy were included (intervention, n = 33; control, n = 33). The patients in the intervention group were given 400 mL of oral liquid carbohydrate 2 hours before surgery. Blood samples were collected from the two groups with serum CRP and albumin levels measured 2 hours before surgery and 24 hours postoperatively. FindingsCRP levels in the intervention group 2 hours before surgery and 24 hours postoperatively were higher than the control group (P = .028; P = .014, respectively). CRP levels of the patients in the intervention group 24 hours postoperatively (26.98 ± 18.60 mg/L) were higher than the preoperative level (9.37 ± 15.68 mg/L) (P < .001). The CRP level of the patients in the control group 24 hours postoperatively (16.24 ± 16.01 mg/L) was higher than the preoperative level (3.11 ± 3.12 mg/L) (P < .001). There was no difference between the serum albumin levels of the patients in the intervention and control groups measured 24 hours postoperatively (P = .103). ConclusionsWe determined that 400 mL oral liquid carbohydrate given preoperatively had no anabolic effect on serum CRP and albumin levels.