Abstract

To evaluate the effect of various perinatal factors, 4,068 cord samples were assayed for T4 concentration, and each chart reviewed for the following factors: Cesarean section (CS), prolonged rupture of membranes (PROM), asphyxia (A), meconium stained amniotic fluid (MS), maternal diabetes mellitus (IDM), and twinning (T). The neonate was evaluated for respiratory distress (RDS) and low (SGA) and high (LGA) birth weight for gestational age. The infants were grouped by gestational age (GA) and compared to normal values (N).Only the SGA infant had a significantly lower mean cord T4 level (p<.01). Conclusions: 1) Within a given GA group, perinatal factors do not affect the mean cord T4 level. 2) The mean cord T4 level increases with GA.

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