Abstract
PP-31-068 Background/Aims: This study was performed to estimate the effects of parental factors on blood lead levels among their children. Methods: We examined the relation between parental factors (eg, parental cotinine level and parental blood lead level) and their children's blood lead levels in a longitudinal study. Sixty-eight children (42 boys and 26 girls) and 101 of their parents were tested for blood lead levels change during the 2 years time period. We also estimated urinary cotinine levels of children and their parents. Results: Geometric mean blood levels were 2.08, 2.22, 1.87 μg/dL for children (aged, 3–19) with total, male, female, respectively. In the multiple regression model, the change of blood lead level was related to father's smoking status after adjusting for age, sex, parental urinary cotinine level, parental blood lead levels, parental blood lead levels change. Blood lead levels change in childhood, especially in boys, was significantly associated with father urinary cotinine levels (P = 0.0012) and blood lead levels change in their mothers (P = 0.0006). Conclusion: This trend may be attributed to differences in blood lead level change among children, especially boys, because of differing smoking status of the father, and blood lead levels change in the mother.
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