Abstract
An experimental model is described in which two splenotomy sites are made in the spleen. In one site oxidized regenerated cellulose (ORC) was placed, in the other absorbable gelatin sponge (AGS). The animals were then challenged intravenously and the number of organisms from the splenotomy sites was measured over a period of time. The number of organisms isolated from the ORC site remained low during the 20 days of the study. The number of organisms from the AGS site was high, in the range of 10 6/ml.
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