Abstract
For the same reasons that we concluded the pyloric action was motivated locally through duodenal stimulation by chemical action, we conclude that this same mechanism is influenced by physical stimuli as represented by changes in osmotic pressure away from isotonicity. Gastric emptying time alone cannot be used as an index of pyloric function when considering osmotic tension of agents given by mouth because of the migration of fluid which takes place through the stomach wall when the test meals are not isotonic.
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