Abstract

Turmeric has a bioactive compound namely curcuminoid. It has many pharmacology effects such as anticancer, antidiabetic, antioxidant, hypolipidemic, anti-inflammatory, antimicrobial, antifertility, anti-venom, anti-coagulant, anti-HIV hepatoprotective, nephroprotective, and anticoagulant properties. To increase the economic value of turmeric, it is necessary to develop a hydrothermal extraction process of turmeric’s active compound. The advantages of hydrothermal extraction were inexpensive, abundant availability, high purity, non-toxic, and easy to handle. This research aims to study the effect of operating conditions : temperature (130-150oC), time (10-40 minutes) and solid:liquid ratio (1:10 and 1:12) on the bioactive compounds of turmeric extracted from hydrothermal extraction process. Generally, high extraction yield was obtained at higher extraction temperature (140 and 150oC). Under these conditions, with a lower solid : liquid ratio (1:10), high concentration of curcumin is produced. Further, a higher solid : liquid ratio will likely produce the opposite result, except when it operates at low extraction temperature. The high temperature of the pressurized liquid water can reduce the viscosity and surface tension of water so it will increase the diffusion rates and absorption. The higher the solid:liquid ratio, the greater the different concentration between interior and exterior cell, which promote the high efficiency of diffusion process.

Highlights

  • Turmeric (Curcuma domestica Val) has many pharmacology effects such as anticancer, antidiabetic, antioxidant, hypolipidemic, anti-inflammatory, antimicrobial, antifertility, anti-venom, anti-coagulant, anti-HIV hepatoprotective, nephroprotective, and anticoagulant properties[1,2,3,4]

  • Hydrothermal extraction of turmeric has been done at a temperature of 130-1500C extraction time of 10-40 minutes, and solid:liquid ratio (1:10 and 1:12) at a fixed pressure of 2 bar

  • The results showed that at a solid liquid ratio of 1:10 and temperature of 130oC, the concentration of curcumin produced in 10 minutes was 17.25% w

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Summary

Introduction

Turmeric (Curcuma domestica Val) has many pharmacology effects such as anticancer, antidiabetic, antioxidant, hypolipidemic, anti-inflammatory, antimicrobial, antifertility, anti-venom, anti-coagulant, anti-HIV hepatoprotective, nephroprotective, and anticoagulant properties[1,2,3,4]. The main bioactive component of turmeric which shows the pharmacological properties mentioned above is curcuminoid[1,2,3,4]. The development of "active compound extracts" production process is an effort that will have high competitiveness which can play an important role in increasing the nation's independence towards drug raw material fulfillment. It increases the product’s prices up to 80.8 times higher than the crops [6]

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