The effect of NovaBone combined with autologous iliac in the acetabular osteotomy of children with developmental dislocation of the hip

Abstract

Objective To compare the effect of application of autologous iliac alone and NovaBone combined with autologous iliac in the acetabular osteotomy of children with developmental dislocation of the hip (DDH). Methods Data of 113 cases of children with DDH who had undergone open reduction and acetabular osteotomy surgery from 2007 to 2011 were retrospectively analyzed. According to bone material using after acetabular osteotomy, the patients were divided into autogenous iliac bone graft group (52 cases, 60 hips) and NovaBone combined with autologous iliac bone graft group (61 cases, 67 hips). There were no statistical differences in gender, age, side, dislocation type, osteotomy and acetabular index between the two groups. The patients were evaluated by Lane's scoring criteria, Severin standards and McKay standards at 6 weeks, 3 months, 6 months, 1-year and 2-year post-operation follow-up. The bone healing of acetabular osteotomy zone, radiography and function of hip were compared. Results 6 weeks and 3 months after operation, Lane bone healing score in NovaBone combined with autologous iliac bone graft group (6.4± 1.3 points and 9.6±1.7 points respectively) was obviously superior to autogenous iliac bone graft group (4.7±1.5 points and 7.8±1.2 points respectively). And 6 months and 1 year after operation, the two groups were basically reached bone healing. The Severin standard results showed that the rate (94%, 63/67) of Excellent and Good in NovaBone combined with autologous iliac bone graft group (excellent: 41 hips, good: 22 hips, Fair: 4 hips) was significantly higher than the rate (83.3%, 50/60) in autogenous iliac bone graft group (excellent: 28 hips, good: 22 hips, Fair: 10 hips). The rate (16.7%, 10/60) of Fair in autogenous iliac bone graft group was significantly higher than the rate (6.0%, 4/67) in NovaBone combined with autologous iliac bone graft group. McKay standard results were consistent with the results of radiological evaluation. Conclusion As a novel bone defect repair material, NovaBone can promote early bone healing process of acetabular osteotomy areas. It also can improve the resistance of osteotomy area. NovaBone can get a satisfied result in acetabular osteotomy in children with DDH. Key words: Hip dislocation, congenital; Child; Osteotomy