Abstract
The effect of natural secretin (G.I.H.) and synthetic secretin (Wünsch) on the secretion of insulin was investigated. Natural as well as synthetic secretin causes a short uniphasic release of insulin without influence on the concentration of glucose in the serum. Since the insulin releasing effect on synthetic secretin was demonstrated, it is clear, that the release of insulin by preparations of natural secretin mentioned in medical literature is not due to contamination by other peptides.
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