Abstract
In our study, metal nanoparticles Ag, Cu, ZnO, CdO and Sn NPs were prepared by pulse laser ablation inliquid and characterized for investigation of reproductive toxicity in adult male rats. Thirty six healthy rats,two month age oldand the rats weighing from 250-300 g, divided into six groups of six animals each (GAg,GCu, GZnO, GCdO and Sn) group which receive oral 0.3 ml dose of metal nanoparticles for 30 day. Bloodsamples were collected via cardiac puncture for serum collection. The formation Ag NPs, Cu NPs, ZnONPs, CdO NPs, Sn NPs were shown through the x-ray diffraction pattern.AFM indicate to formation metalnanoparticles with diameter 61.36, 70.44, 66.82, 74.87 and 67.34 nm of Ag, Cu, ZnO, CdO and Sn NPsrespectively.The results showed significant (P<0.05) elevation of luteinizing hormone (LH) for each metalnanoparticles except AgNPs non- significant .each metal nanoparticle significant (P<0.05 and ** p?0.01)offollicle-stimulating hormone(FSH), whereas in testosterone only Cu and Sn NPs significant (P<0.05).
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