Abstract

The purpose of the research is to determine the etiopathogenesis of reproductive dysfunction in highly productive cows. For this, one group of cows was formed on the principle of paranalogs in the amount of 37 animals inseminated in the first sexual hunt after calving, followed by taking blood samples from them using the Monovet system, considering the duration of pregnancy. During the start-up period, blood was taken 1–4 days before calving and on the first day after calving. A total of 253 blood samples were examined. Subsequently, depending on the effectiveness of insemination, animals were divided into two groups. The first group included inseminated cows after the first insemination (20 animals), the second group included 17 unfertilized cows after the first insemination. Subsequently, blood was taken from animals considering the course of childbirth and the postpartum period. Blood counts were studied according to generally accepted methods using certified equipment. The study found that at an early stage of pregnancy, cows have a significant difference in lipid metabolism and in their peroxidation, in the state of antioxidant systems compared to unstable animals. In the process of pregnancy development in cows, there is a decrease in the level of total lipids and their class, and the accumulation of products of transoxidation of lipids is reduced. In animals with retention of the placenta, a low lipid metabolism and a higher level of peroxidation were established already in the dry period. After calving, this difference increases. The obtained data can be used to develop an algorithm for the prevention of postpartum complications in cows by using substances with antioxidant properties.

Highlights

  • The main task of intensifying dairy cattle breeding is to increase the level of animal milk production, which largely depends on the feeding conditions during preparation for calving and after calving

  • In the class composition of lipids, the most significant difference was found in the content of nonesterified fatty acids (NEFA), triglycerides and cholesterol, both free and ether bound

  • According to domestic and foreign researchers, pregnancy and the birth that follows, restoration of the reproduction function after childbirth in mammals is accompanied by changes in metabolism to hidden forms of its violation

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Summary

Introduction

The main task of intensifying dairy cattle breeding is to increase the level of animal milk production, which largely depends on the feeding conditions during preparation for calving and after calving. That is especially important for industrial milk production technology, since it requires preparation for insemination, calving not individual animals, and a large number of their analogues – by age, gestational age. When preparing highly productive cows for calving and subsequent lactation, it is important to establish a feeding level that ensures lipid metabolism, both for your own body and for creating a reserve of nutrients in the mother's body for the postpartum period and future lactation. Microbial digestion of fiber and other nutrients in the gum stomachs of the ruminants indicates the nature of the influence of the formed and used metabolites of the substrate [1]. The main precursor of high molecular weight fatty acids in ruminants is acetate [2, 3]

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