Abstract
Facial ageing is a gradual process which could be due to intrinsic and extrinsic causes, it ultimately results in the appearance of gravity-induced tissue ptosis, wrinkles, epidermal and dermal atrophy, dryness, senile lentigo, flushing, telangiectasia, and enlarged pores. Mesobotox treatment is a technique of microinjections of diluted Botulinum toxin type A (BTX) to preserve the facial mobility in order to preserve the natural beauty. BTX treatment enhances the aesthetic improvements attained with IPL. Ten patients of age ranging between 40 - 60 years old ( mean 45±10.3 years) with skin type ranging between (III - V) were treated using BTX and Intense Pulsed Light (IPL) using cutoff filter 550 nm with a fluence of 25 J/cm2 together as a combination therapy. All patients received standard IPL treatment and were assigned to receive eight 0.1 mL intradermal injections of BTX in each cheek (8 U total dose). Vertical lines within the forehead also received five 0.1 mL intradermal injections of BTX. Small wrinkles and fine lines, erythema, apparent pore size, skin texture, and overall appearance were evaluated after one week. A significantly higher proportion of patients showed improvement in small wrinkles and erythema with IPL plus BTX compared with the baseline demonstrated by computerized image analysis. In conclusion, A combined therapy of mesobotx and IPL is an effective and safe treatment for fine wrinkles, telangiectasia, flushing.
Highlights
As life expectancy has prolonged nowadays, interest has increased to change patterns of life, which include improving the consequences of skin ageing through slowing the ageing process
Small wrinkles and fine lines, erythema, apparent pore size, skin texture, and overall appearance were evaluated after one week
All patients showed at least mild improvement from baseline in small wrinkles and fine lines which was significantly greater after Intense Pulsed Light (IPL)-Botulinum toxin type A (BTX) treatment in relation to the base line depending on the skin type
Summary
As life expectancy has prolonged nowadays, interest has increased to change patterns of life, which include improving the consequences of skin ageing through slowing the ageing process. There are two main process of skin ageing either intrinsic or extrinsic. Intrinsic ageing reflects genetic background in which skin appears thin with exaggerated expression lines. Extrinsic ageing is caused by external factors such as smoking, excessive use of alcohol, poor nutrition and sun exposure. Aged skin appears predominately by wrinkles, and by pigmented lesions such as freckles, lentigines and patchy hyperpigmentation, and depigmented lesions such as guttate hypomelanosis. Rough skin texture, flushing, erythema, telangiectasias, dilated pores and loss of tone and elasticity are other signs of skin aging [1]
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