Abstract
Serum cholesterol levels in Pima Indian women were investigated to determine if menopause caused these levels to rise. The mean cholesterol values of 148 pre-menopausal women aged 34-54 when age-matched with 75 post-menopausal women were not significantly different. Sixty-five women passed through menopause while under observation and were examined sequentially for an average of 6.1 years. Their mean pre- and post-menopausal cholesterol levels of 182 +/- 5 mg/100 ml and 180 +/- 5 mg/100 ml were similar. Nor did menopause alter cholesterol levels in the subgroups of these patients with diabetes mellitus. Cholesterol levels in both Pima males and females showed no age-related rise, and were 20-30% lower than white populations. This study provides additional evidence against the postulated relationship between menopause and serum cholesterol.
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