Abstract

A study was made of the effect produced by mechanical injury of the brain cortex (application of gauze tampons to the premotor and occipital areas under the dura mater of both hemispheres) on the adrenocorticotropic function in dogs. Changes in the latter function were assessed by the shifts in the androgen level in the adrenal cortex of hypophysectomized rats-recipients to which an extract of hypophysis of intact and experimental donor-dogs was administered. The initial androgen level in the recipient's adrenal glands was determined (for comparison) by its content in the left adrenal gland excised prior to the injection of the extract.

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