Abstract
Objectives This study investigated the effects of low intensity pulsed ultrasound (LIPUS) on dentoalveolar structures during orthodontic force application using a novel organ culture system. Methods Mandibles were dissected from 28-day-old male Sprague Dawley rats, sliced into 1.5 mm and cultured at 37 °C and 5% CO 2, prior to application of a 50 g force to each mandible slice. Slices were randomly divided into three groups of control, 5 and 10 min LIPUS application and cultured for five days before histological and histomorphometrical analysis. Results Cementum and predentine thickness and subodontoblast and periodontal ligament cell counts were increased in the ultrasound groups, with increases statistically significant in the 10 min treated groups. Odontoblasts remained viable during LIPUS exposure and osteoclast activity was increased by LIPUS. Conclusions LIPUS may influence remodelling of the dentine–pulp complex and associated tissues during orthodontic force application ex vivo.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
