Abstract

The aim of this study was to determine the effect of low-dose propofol on the respiratory complications immediately after tracheal extubation in children undergoing tonsillectomy. In this randomized double blinded clinical trial study, 70 children (2-12) years old with ASA class I undergoing elective tonsillectomy involved. General anesthesia was performed by the same anesthesiologist and in the same way. The patients were then intubated with oxygen after 3min of ventilation. After the surgery and muscle relaxant injection and before extubation, 0.5mg propofol/kg was injected into the intervention group. The control group received normal saline. Finally, the presence of post-extubation laryngospasm, cough and nausea and vomiting was recorded and all data analyzed between two groups. There was no significant difference in age (p value = 0.425), gender (p value = 0.851), cough (p value = 0.239), nausea (p value = 1) and weight (p value = 0.624) between two groups. There was a significant different in incidence of laryngospasm between two groups (p value = 0.04). It can be concluded that the administration of 0.5mg/kg of propofol before extubation could prevent laryngospasm in patients undergoing tonsillectomy, without inducing any side effects.

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