Abstract
Various aspects of pulmonary function were measured in eight patients with chronic bronchial obstructive disease, after five-month oral administration of a sustained-release aminophylline preparation (BY 108: Euphyllin retard). In addition to a sustained bronchodilator effect there was an improvement in static pulmonary volumes and a marked increase in forced expiratory volumes. The reduction in residual volume and of midcapacity is felt to be of particular importance in the prevention of pulmonary emphysema.
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