The effect of local anaesthetic on post-operative pain with wound instillation via a catheter for paediatric orthopaedic extremity surgery

Abstract

We aimed to investigate the effects on post-operative pain of local anaesthetic administration via a catheter placed into the operation site in patients who were undergoing upper and lower extremity paediatric orthopaedic surgery. In this randomised, double-blind and placebo study, 40 ASA I-II patients aged between 1 and 12years were randomly allocated into two groups: study group (Group S: 0.2 ml/kg, 0.5% bupivacaine, n=20) and control group (Group C: 0.2 ml/kg, serum physiologic, n=20). Before the fascia was closed by the surgical team, the solution previously prepared by the chief nurse was injected into the subfascial soft tissue with the syringe as the "injected dose" of serum physiologic or bupivacaine. After the closure, 0.2ml/kg (1mg/kg) bupivacaine or saline was instillated as the "first instillated dose" into the surgical area via the catheter. Pain scores were recorded at 0, 1, 2, 4, 8, 12, 24 and 48h post-operatively. Patients were administered 0.75mg/kg meperidine intramuscularly post-operatively to equalise the pain scores. No statistically significant difference was found between Group S and Group C in terms of demographic and other data and pain scores in the post-anaesthesia care unit, while a statistically significant decrease was found at 2, 4, 8, 12, 24 and 48h in Group S and at 1, 2 and 4h in Group C based on pain scores in the post-anaesthesia care unit (P<0.05). A statistically significant decreasing pain score was found at 4, 8, 12, 24 and 48h in Group S (P<0.05). The local anaesthetic administered via a catheter implanted in the surgical field may provide long-term and efficient post-operative analgesia.