Abstract
Objective: The effect of lead and other environmental pollution due to heavy metals is one of man's major problems in the health sector. This paper aims at evaluating the physiological effect of lead in albino mice as a relative measure of estimating leads non beneficial property in man. Methodology: Albino mice were reared in cages and fed adlibitum in the laboratory for two weeks before lead sulphate was administered into their food, water, food and water and in the surrounding. Control mice were fed with normal food and water (no lead added) at the same time of treatment. Result: Of the total number of mice subjected to treatment (n=30) with lead sulphate 12 died of lead poisoning. The percentage mortality rate recorded was 33.3%. It was also recorded that albino mice in treatments GBX, GBW and GBY had their weight reduced by -12.9g, -18.0g and -8.7g respectively. The mice in the control treatment did not suffer weight loss rather they increase in weight by 20.7g. the effect of lead by inhalation also showed mild effect even though there was slight weight increase (6.6g) and low percentage mortality (8.7%). Conclusion: The physiological and psychological effect of lead and other environmental consequences of lead pollution are highlighted.
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