Abstract
Rats of the Royal College of Surgeons (RCS) strain undergo retinal degeneration within their first postnatal months. In this study, brightness detection thresholds for white and colored stimuli were measured in RCS rats using the behavioral method of conditioned suppression. Despite their retinal degeneration, RCS rats reared in cyclic light showed only a small visual deficit. Dark reared RCS rats had thresholds equal to those of nondystrophic albino rats. When exposed to continuous illumination, however, RCS rats raised in cyclic light showed severe visual deficits not incurred by nondystrophic albinos exposed to the same conditions.
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