The effect of ischemic preconditioning on the course of polyneuropathy in vibration disease

Abstract

One of the primary syndromes of vibration disease is polyneuropathy, which is characterized primarily by the involvement of sensory fibers. In the clinical picture, such a lesion manifests itself in the form of sensitive disorders (pain, numbness, paresthesia), which worsen patients' quality of life. The neuroprotective effect of ischemic preconditioning is currently insufficiently studied and is a promising area of scientific research. The study aims to learn the effect of ischemic preconditioning of the upper extremities on the clinical and neurophysiological manifestations of polyneuropathic lesion in vibration disease. Scientists examined 70 patients with an established diagnosis of vibration disease (40 people - the leading group and underwent ischemic preconditioning of the upper extremities, 30 people - the control group, they did not use this technique. All subjects underwent clinical and electroneuromyographic examinations before ischemic preconditioning on the 5th day of the study. The initial indicators of the examination in both groups did not differ statistically and had signs of the polyneuropathic lesion. However, after ischemic preconditioning, clinical symptoms significantly decreased, the speed of conduction along sensory fibers increased, but we did not find significant objectivity of dynamics in the control group. Ischemic preconditioning of the upper extremities in vibration disease leads to a decrease in the severity of the clinical and neurophysiological picture of the polyneuropathic lesion.