Abstract
Cell division via mitosis is one of the most important biological processes to sustain life. Microtubules, along with their associated proteins, crosslinkers, and enzymes, play a crucial role in the formation of the mitotic spindle. Previous studies on self-organization of microtubules showed that, in presence of polymer crowding agents, microtubules self-organize into bundles. Introducing certain concentrations of an antiparallel crosslinker, MAP65, in the system resulted in the bundles coalescing into homogenous, birefringent tactoids.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have