The effect of intravenous morphine compare to lidocaine on renal colic patients in emergency department

Abstract

Introduction: The aim of this study was to compare the effect of intravenous morphine versus lidocaine on renal colic in patients admitted to the emergency department. Methods and Materials: In this clinical trial study, 80 patients with renal colic admitted to the emergency department were included. Patients were divided into two groups randomly, namely Lidocaine and morphine groups. Each patient’s pain score was recorded 5, 10, 15 and 30 minutes after the injection using Numeric Pain Intensity Scale (NPIS). Results: There were significant decreases in mean of pain scores in both groups (p <0.001). Pain reduction was significantly higher in Lidocaine-received group at 30th minutes after injection (p <0.001). Having compared groups in terms of complications, it was found that only dizziness in patients who received Lidocaine was significantly higher than that of the other group (p = 0.016). Conclusion: Considering the significant reduction in pain intensity of all patients, the effect of both medications on the reduction of pain in renal colic is confirmed. Given that pain relief in Lidocaine group was significantly more than that in morphine group after 10 minutes of injection, it can be concluded that Lidocaine is more effective than morphine in controlling renal colic.