Abstract
The apparently low incidence of respiratory distress syndrome in babies born prematurely after intrauterine transfusion and the simultaneous prophylactic administration of intravenous isoxsuprine (a beta-sympathomimetic agent) was investigated by serial study of amniotic fluid lecithin/sphingomyelin ratios. The ratio rose very significantly after intrauterine transfusions and significantly (but less markedly) after the administration of intravenous isoxsuprine alone.
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