Abstract
Stroke volume variation (SVV) has been used to predict fluid responsiveness; however, it remains unclear whether goal-directed fluid therapy using SVV contributes to bowel function recovery in abdominal surgery. This prospective randomized controlled trial aimed to compare bowel movement recovery in patients undergoing colon resection surgery between groups using traditional or SVV-based methods for intravenous fluid management. We collected data between March 2015 and July 2017. Bowel function recovery was analyzed based on the gas-passing time, sips of water time, and soft diet (SD) time. Finally, we analyzed data from 60 patients. There was no significant between-group difference in the patients’ characteristics. Compared with the control group (n = 30), the SVV group (n = 30) had a significantly higher colloid volume and lower crystalloid volume. Moreover, the gas-passing time (77.8 vs. 85.3 h, p = 0.034) and SD time (67.6 vs. 85.1 h, p < 0.001) were significantly faster in the SVV group than in the control group. Compared with the control group, the SVV group showed significantly lower scores of pain on a numeric rating scale and morphine equivalent doses during post-anesthetic care, at 24 postoperative hours, and at 48 postoperative hours. Our findings suggested that, compared with the control group, the SVV group showed a faster postoperative SD time, reduced acute postoperative pain intensity, and lower rescue analgesics. Therefore, SVV-based optimal fluid management is expected to potentially contribute to postoperative bowel function recovery in patients undergoing colon resection surgery.
Highlights
Fluids are administered during intestinal resection based on several factors, including preoperative fasting time, intraoperative bleeding, blood pressure maintenance, and loss of one-third volume of water
We evaluated the occurrence and types of postoperative complications, whether the patient was transferred to the intensive care unit (ICU), the number of days of postoperative hospital stay, and whether the patient died within the study period
This study evaluated the utility of Stroke volume variation (SVV) for intraoperative fluid management in patients undergoing colorectal cancer surgery by comparing prognosis, including intestinal motility recovery and surgical complications
Summary
Fluids are administered during intestinal resection based on several factors, including preoperative fasting time, intraoperative bleeding, blood pressure maintenance, and loss of one-third volume of water. Excessive intraoperative fluid administration leads to poor outcomes, including increased postoperative bowel edema, respiratory complications, and longer durations of hospital stay. Goal-directed fluid supply is warranted since optimal intraoperative supply of fluids improves postoperative recovery and prognosis [1,2,3]. Optimal fluid replacement therapy during major abdominal surgery remains unclear. There are possible negative or positive interactions between fluid therapy and gastrointestinal (GI) function. Inadequate fluid management may cause delayed GI function recovery and may prevent early oral intake. Postoperative GI dysfunction may cause electrolyte loss and metabolic problems [3]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
