The effect of Intermittent fasting on the growth and ghrelin hormone in rats feeding on a standard diet

Abstract

Aim: In this study, the effect of intermittent fasting on growth hormone (GH) and ghrelin was examined in rats that fed on a standard diet without any application that may cause the values to decrease or increase in order to see the net effect of intermittent fasting. Materials and Methods: 12 Wistar albino male rats were divided into the 1st group as Control (standard diet 2.8% crude fat. 23.1% crude protein. 5% crude fiber. 7.1% crude ash and 12.8% moisture) and the 2nd group as the intermittent fasting together with the diet group (with a 24-hour break from the non-consecutive diet for 2 days a week and all food restricted except water). Results: As a result of the analysis, it was found that the growth hormone in the intermittent fasting together with the standard diet group tended to increase compared to the control group, and while this value difference was not statistically significant, the ghrelin level was found to be statistically lower than the control group. Conclusion: As a result, it was found that intermittent fasting tends to increase the level of growth hormone, and to have a decreasing effect on ghrelin level, and it was concluded that it can be considered among the methods to be used to treat obesity and prevent its occurrence.