The effect of intense physical activity session with glutamine supplementation on selected factors of wrestlers' immune system

Sepehri Manesh Mohammad Sepehri Manesh Mohammad,Sohrabi Parisa Sohrabi Parisa,Abbasi Moghadam Mahdi Abbasi Moghadam Mahdi

doi:10.30574/ijsra.2021.2.2.0070

Sepehri Manesh Mohammad Sepehri Manesh Mohammad, Sohrabi Parisa Sohrabi Parisa + Show 1 more

Open Access

https://doi.org/10.30574/ijsra.2021.2.2.0070

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Abstract

Athletes with heavy training loads are prone to infectious diseases. It has been shown that these exercises may suppress immune function. The aim of this study was to investigate the effect of one session of intense physical activity with glutamine supplementation on selected factors of wrestlers' immune system. For this purpose, 20 wrestlers were selected and randomly divided into two groups of supplement and placebo. The first blood sample was taken from the subjects. Then they did the Bruce test. Immediately after the end of the test, blood samples were taken from the subjects for the second time and then to the supplement group. The glutamine supplement was given the same amount of maltodextrin per kilogram of body weight and the placebo group. Blood samples were taken from the subjects for the third and fourth time 1 and 2.5 hours after taking the supplement or placebo. After measuring blood factors, the findings were statistically analyzed (ANOVA) at a significance level of p <0.05. The results showed that the percentage of neutrophils in the supplement group increased significantly 2.5 hours after supplementation compared to immediately after exercise and 1 hour after supplementation. This increase was less in the supplement group than in the placebo group. The percentage of lymphocytes in the supplement group decreased significantly 2.5 hours after supplementation compared to the pre-test, immediately after exercise and 1 hour after supplementation, which was less in the supplement group than the placebo group. The percentage of monocytes in the supplement group increased significantly 2.5 hours after supplementation compared to immediately after exercise. This increase was less in the supplement group than in the placebo group. The results of this study showed that glutamine supplementation during strenuous exercise has beneficial effects on the immune system of athletes.

Highlights

The function of the human body is affected by different systems
The results of this study showed that glutamine supplementation during strenuous exercise has beneficial effects on the immune system of athletes
The aim of the present study was to investigate the effect of glutamine supplementation on selected immune system factors of wrestlers following a session of intense physical activity

Summary

Introduction

The function of the human body is affected by different systems. Exercise activities of varying intensity and duration cause a variety of responses in these systems. The immune system is one of the systems that undergoes major changes as a result of sports activities. The most important function of the immune system is to protect the body against infectious diseases [1]. While moderate-intensity physical activity has beneficial effects on the immune system, intense exercise reduces the function of the immune system [2]. Studies show that during intense exercise, the incidence of infectious diseases, especially upper respiratory tract infections, increases [3]. Changes in metabolic factors during exercise, such as decreased plasma glutamine, can play an important role. Research shows that lymphocyte density decreases during strenuous exercise [4]

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