Abstract
Summary Lymphocyte blastogenesis and serum cortisol concentrations were measured in intensely exercised horses. Four mature Quarter Horse mares were exercised to fatigue on a motorized treadmill. Blood samples were taken at rest, 15 minutes, 30 minutes, and 24 hours post-exercise. Peripheral blood mononucleocytes were isolated and cultured with 2 T cell mitogens, concanavalin A (Con A), and phytohemagglutinin (PHA) to induce proliferation of responsive T cell lymphocytes. In addition, serum cortisol concentrations were measured via a radioimmunoassay. The results reveal a significant suppression of the blastogenic response to Con A (P
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