The effect of infusing noradrenaline or of stimulating the sympathetic nerves on the blood pressure response to indirect sympathomimetics.

Abstract

British Journal of Pharmacology and ChemotherapyVolume 30, Issue 1 p. 99-107 Free Access THE EFFECT OF INFUSING NORADRENALINE OR OF STIMULATING THE SYMPATHETIC NERVES ON THE BLOOD PRESSURE RESPONSE TO INDIRECT SYMPATHOMIMETICS J. S. GILLESPIE, J. S. GILLESPIE Institute of Physiology and Division of Experimental Pharmacology, The University, Glasgow Henry Head Fellow.Search for more papers by this authorT. C. MUIR, T. C. MUIR Institute of Physiology and Division of Experimental Pharmacology, The University, GlasgowSearch for more papers by this author J. S. GILLESPIE, J. S. GILLESPIE Institute of Physiology and Division of Experimental Pharmacology, The University, Glasgow Henry Head Fellow.Search for more papers by this authorT. C. MUIR, T. C. MUIR Institute of Physiology and Division of Experimental Pharmacology, The University, GlasgowSearch for more papers by this author First published: May 1967 https://doi.org/10.1111/j.1476-5381.1967.tb02116.xCitations: 6 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL REFERENCES Axelrod, J. (1964). The uptake and release of catecholamines and the effect of drugs. Progress in Brain Research, 8, 81– 89. Brown, L. (1965). The release and fate of the transmitter liberated by adrenergic nerves. Proc. R. Soc. (B), 162, 1– 19. BÜLBRING, E. & Burn, J. H. (1942). An action of adrenaline on transmission in sympathetic ganglia, which may play a part in shock. J. Physiol., 101, 289– 303. Burn, J. H. & Rand, M. J. (1958). The action of sympathomimetic amines in animals treated with reserpine. J. Physiol., 144, 314– 336. Dahlström, A. B. & Zetterström, B. E. M. (1965). Noradrenaline stores in nerve terminals of the spleen: changes during haemorrhagic shock. Science, N.Y., 147, 1583– 1585. DE Schaepdryver, A. F., Bogaert, M., Delaunois, A. L. & Bernard, P. (1963). Peripheral noradrenergic reactivity. Archs int. Pharmacodyn. Ther., 142, 243– 259. Duner, H. & Von Euler, U. S. (1957). Secondary fall in blood pressure following noradrenaline infusion in the cat. Acta physiol. scand., 38, 355– 363. Gillespie, J. S. & Muir, T. C. (1965). Desensitisation of vascular smooth muscle to infused noradrenaline and to tyramine. Communication to British Pharmacological Society, Jan., 1965. Gillespie, J. S. & Hamilton, D. N. H. (1966). Binding of noradrenaline to smooth muscle cells in the spleen. Nature, Lond., 212, 524– 525. Gillespie, J. S. & Muir, T. C. (1967a). A method of stimulating the complete sympathetic outflow from the spinal cord to blood vessels in the pithed rat. Br. J. Pharmac. Chemother., 30, 78– 87. Gillespie, J. S. & Muir, T. C. (1967b). The origin of the decline in the vasopressor response to infused noradrenaline in the pithed rat. Br. J. Pharmac. Chemother., 30, 88– 98. Goldstein, A. (1949). The interactions of drugs and plasma proteins. Pharmac. Rev., 1, 102– 165. Marrazzi, A. S. (1939). Adrenergic inhibition at sympathetic synapses. Am. J. Physiol., 127, 738– 744. Muscholl, E. (1966). Indirectly acting sympathomimetic amines. Pharmac. Rev., 18, Part i, 551– 559. Nasmyth, P. A. (1962). An investigation of the action of tyramine and its interrelationship with the effects of other sympathomimetic amines. Br. J. Pharmac. Chemother., 18, 65– 75. Paton, W. D. M. (1961). A theory of drug action based on the rate of drug-receptor combination. Proc. R. Soc. B., 154, 21– 69. Raab, W. & Gigee, W. (1955). Specific avidity of the heart muscle to absorb and store epinephrine and norepinephrine. Circulation Res., 3, 553– 558. Weiner, N., Draskóczy, P. R. & Burack, W. R. (1962). The ability of tyramine to liberate catecholamines in vivo. J. Pharmac. exp. Ther., 137, 47– 55. Trendelenburg, U. (1966). Mechanisms of supersensitivity and subsensitivity to sympathomimetic amines. Pharmac. Rev., 18, 629– 640. Citing Literature Volume30, Issue1May 1967Pages 99-107 ReferencesRelatedInformation