Abstract
Intra-amniotic inoculation of influenza C virus resulted in observable and quantitatively measurable changes in the Purkinje cells of chick embryo cerebellum. Purkinje cells were visualized by the Golgi-Cox procedure and prepared for statistical and computer evaluation from camera lucida drawings. Four computer-generated measurements (the area of the dendritic arbor, the perimeter of the dendritic tree, and the height and width of the cell's arborization) and two manually counted measurements (total number of branches and the number of first order branches) were made. Analysis of Purkinje cells from influenza C virus-infected embryos showed disturbances in dendritic arborization patterns and misalignment in the arrangement of the cells in the Purkinje cell layer compared to control cells. Statistical evaluation of Purkinje cell arborization showed significant decreases in all measured parameters for the influenza C virus-infected members when compared with the members of the uninfected control group.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Developmental Neuroscience
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
