Abstract
Abstract Objectives: The objective of the present study was to determine the effect of 10 weeks of high intensity interval training and flaxseed oil supplement on heart IGF-1 concentration in male rats. Materials and methods: 20 adult male Wistar rats were randomly divided into saline, saline–training, supplementation, and supplementation–training groups. The training groups performed training (10 weeks, five sessions per week, 90–95% VO2 max) on a rodent treadmill. The supplementation groups also received flaxseed oil supplement (30 mg/kg). The rats were sacrificed five days after the last training session. The heart tissue was collected, and sent to the laboratory for evaluation. Results: Training increased the concentration of the heart IGF-1 (P=0.01). The concentration of heart IGF-1 was higher in the flaxseed oil-supplemented groups than the saline-treated groups. (P=0.003). The interaction between training and supplementation also led to a increase in heart IGF-1 concentration (P=0.001). Conclusion: The increase of heart IGF-1 after training and consumption suggest that training and flaxseed oil can help to improve cardiac function.
Highlights
The objective of the present study was to determine the effect of 10 weeks of high-intensity interval training (HIIT) and flaxseed oil supplement on heart insulin-like growth factor-1 (IGF-1) concentration in male rats
Two-way analysis of variance (ANOVA) on cardiac IGF-1 showed a significant difference between training group and control group (F = 8.502, P = 0.01)
Training led to a significant increase in IGF-1 concentration in the cardiac tissue
Summary
The objective of the present study was to determine the effect of 10 weeks of high-intensity interval training (HIIT) and flaxseed oil supplement on heart IGF-1 concentration in male rats. Methods: Twenty adult male Wistar rats were randomly divided into saline, saline–training, supplementation, and supplementation–training groups. The heart tissue was collected, and insulin-like growth factor-1 (IGF-1) was measured in the heart tissue. Results: Training increased the concentration of the heart IGF-1 (P = 0.01). The concentration of heart IGF-1 was higher in the flaxseed oil-supplemented group than the saline-treated groups. The interaction between training and supplementation led to an increase in heart IGF-1 concentration (P = 0.001). Conclusion: The increase of heart IGF-1 in trained supplemented group suggests that training and flaxseed oil can help to improve cardiac function. Resistive activities lead to increased thickness of the heart septa, whereas endurance activities increase the volume of the heart cavity.[9]
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have