Abstract
A recent study (1) showed that tumor regression following irradiation was markedly increased by daily injections of distilled water or hypotonic Locke-Ringer solution into the tumor. Swelling of the cells generally followed. It is our belief that the increase in radiosensitivity of a tissue may be due to increase of circulation or a decrease of the osmotic pressure of the surrounding extracellular fluids. It is extremely important to learn the role of fluids in the reactions of irradiated living organisms. This work was planned to determine the significance of water balance in relation to irradiated tumors. The problem was approached by studying the combined effects of roentgen radiation and fever, and roentgen radiation and cold upon transplantable tumors. Effect of High Body Temperature upon The Growth of Irradiated Tumors It is believed that in fever there is a considerable disturbance in the water balance of the body. Thirst exhibited by patients is interpreted as evidence of a demand for water by the...
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