Abstract
Powders of water-cleaned white kaolin were heated at different temperatures (200, 350, 500, 650, 800, and 950°). Changes in the internal structure of kaolin (density and crystal structure) and surface properties (specific surface area, immersion heat, and methylene blue adsorption) were investigated and compared with alterations of the in vitro hemolytic effect—a model of cell damaging effect—of kaolin dusts. Complete dehydration of kaolinite crystals into metakaolinite between temperatures of 500 and 650° was accompanied by complete loss of hemolytic activity. When heating was carried out at higher temperatures, 800 or 950°, the hemolytic effect became more intensive again, as γ-Al 2O 3 (or mullite) and SiO 2 (cristobalite) were formed from metakaolinite. Of the surface properties studied, only methylene blue adsorption was found to be directly correlated with the hemolytic activity. The extent of hemolysis caused by kaolin samples heated at different temperatures depended on the crystal structure and hydration of the surface.
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