Abstract

The experimental results of halothane effect on GAD65/67 positive cells, number in ÑÀ1 and ÑÀ1 fields of white rat hippocampus are presented in the proposed work. It has been shown, that the number of GAD65/67 positive cells are decreased in CA3 field of hippocampus after 24 hours of halothane anesthesia. Simultaneously the number of the same cells are increased in CA1 field of hippocampus. Midazolam premedication promotes normalization of activity of GAD65/67 which is substantiated by increased number of GAD65/67 positive cells in CA3 field of rat hippocampus after 24 hours.

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