The effect of halogen-containing anesthetics on the indicators of the gas composition of the blood of horses

Abstract

The aim of the work was to determine the parameters of the gas composition and acidbase state (CBS) of blood to assess the adequacy of general anesthesia of horses with halogen-containing anesthetics in clinical and instrumental studies. The object of the study was 18 horses aged four to six years, which were castrated. The paper compared the dynamics of blood gas composition indicators at various stages of inhalation anesthesia with fluorotane, isoflurane and sevoflurane in order to prevent and timely detect hypoxemia and hypercapnia in horses. Based on a comprehensive assessment of the clinical examination data, laboratory studies of the gas composition of arterial blood, objectively determine the severity of hypoxemia and hypercapnia, which made it possible to provide the necessary assistance to the animal in a timely manner. The study of blood gas composition indicators has established that the amount of carbon dioxide tension in arterial blood (РaСO2) with both types of anesthesia is subject to the greatest changes during induction and during awakening. During the induction period, it increased both with the inhalation of fluorotane and with the use of isoflurane and sevoflurane, respectively, by 41%, 3.1% and 3.4% compared to the initial values. During the period of awakening, the value of РaСO2 returned to the initial level with anesthesia with isoflurane, with anesthesia with sevoflurane and fluorotane remained above the initial values by 21.8% and 42.8%, respectively. Early detection of signs of hypoxemia and hypercapnia made it possible to avoid the development of further complications during general anesthesia in horses