Abstract

Gum arabic is a polysaccharides obtained from the stems and branches of Acacia senegaltree. In folk medicine Gum arabic has been reported to have anti-oxidant and nephroprotectant effects. This study aimed to evaluate the Gum arabic effect on kidney dysfunction in chickens which induced by cadmium nitrate. Healthy chickens were divided into three groups, 5 chickens in each group; group 1: Normal group fed on basal diet, group 2: Control group feed on basal diet mixed with (100 ml/kg b. w.) cadmium nitrate, Group 3: Treated group, chickens feed on basal diet mixed with cadmium nitrate (100 ml/kg b. w.) then treated with Gum Arabic extract (500 g/kg body weight). . Blood samples were collected at the beginning of the experiment (group 1: normal), after 5 days blood samples collected from (group 2: control) and after 10 days of Gum Arabic treatment blood samples collected from (group 3: treated), creatinine and uric acid were estimated as a kidney function parameters. The results demonstrated that oral administration of cadmium nitrate (control group) recorded a significant increase at (p Furthermore, the results obtained from this study suggested that oral administration of Gum Arabic extract may be helpful in the prevention of kidney dysfunction and may represent an effective therapy that normalizes serum creatinine and serum uric acid levels in chickens.

Highlights

  • IntroductionGum Arabic is a dried exudate obtained from the stems and branches of AcaciaSenegal tree, consists mainly of polysaccharides and it is a pale white to orangebrown solid .Gum Arabic has wide industrial uses as a stabilizer, thickening agent and emulsifier, mainly in the food industry (e.g. in soft drinks syrup, gummy candies, and marshmallows), and in cosmetics and pharmaceutical industries (Verbeken et al, 2003)

  • Gum Arabic is a dried exudate obtained from the stems and branches of AcaciaSenegal tree, consists mainly of polysaccharides and it is a pale white to orangebrown solid .Gum Arabic has wide industrial uses as a stabilizer, thickening agent and emulsifier, mainly in the food industry, and in cosmetics and pharmaceutical industries (Verbeken et al, 2003).Citation: Egypt

  • Group 2: Control group, chickens feed on basal diet mixed with. (100 ml/kg b. w.)Cadmium nitrate Group 3: Treated group, chickens feed on basal diet mixed with (100 ml/kg b. w.) cadmium nitrate treated with Gum Arabic extract (500 g/kg body weight)

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Summary

Introduction

Gum Arabic is a dried exudate obtained from the stems and branches of AcaciaSenegal tree, consists mainly of polysaccharides and it is a pale white to orangebrown solid .Gum Arabic has wide industrial uses as a stabilizer, thickening agent and emulsifier, mainly in the food industry (e.g. in soft drinks syrup, gummy candies, and marshmallows), and in cosmetics and pharmaceutical industries (Verbeken et al, 2003). Physiology and Molecular biology ) Vol 12(1 ) pp.15-21(2020)

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