Abstract
Background. Two prophylactic papillomavirus (HPV) vaccines have been available for primary prevention of cervical cancer. Although serious adverse effects (AE) were rare, more than 230 women have been suffering from severe AEs such as persistent pain and headache in Japan. Our research group started to treat adolescent females suffering from the AEs. Objective. To survey the characteristics of and the effects of cognitive behavioral therapy on adolescent female suffering from the AEs in Japanese multidisciplinary pain centers. Methods. One hundred and forty-five patients suffering from the AEs were reviewed retrospectively and 105 patients of them were provided guidance on home exercise and activities of daily living based partially on a cognitive-behavioral approach. The intensity of pain was rated by the patients using a numerical rating scale (NRS). Furthermore, the Hospital Anxiety and Depression Scale (HADS) and the Pain Catastrophizing Scale (PCS) were used. Results. Eighty out of the 105 patients who received the guidance were followed up, 10 displayed a marked improvement, and 43 showed some improvement. Conclusions. Guidance on home exercise and activities of daily living based on a cognitive-behavioral approach alleviated the AEs that women suffered from after HPV vaccination in Japan.
Highlights
Cervical cancer is the fourth most common cancer in women in the world [1]
We report here the characteristics of and the effects of cognitive-behavioral therapy on women suffering from adverse effects (AE) after human papillomavirus (HPV) vaccination in Japanese multidisciplinary pain centers
The cause of serious symptoms among teenage girls vaccinated with the HPV vaccines and their safety have yet to be verified
Summary
Cervical cancer is the fourth most common cancer in women in the world [1]. Genital infection with human papillomavirus (HPV) types 16 and 18 can cause cervical cancer [2]. Two prophylactic HPV vaccines (quadrivalent and bivalent) have been available for primary prevention of cervical cancer in over 100 countries. Safety of both vaccines has been evaluated [2, 3]. Two prophylactic papillomavirus (HPV) vaccines have been available for primary prevention of cervical cancer. Serious adverse effects (AE) were rare, more than 230 women have been suffering from severe AEs such as persistent pain and headache in Japan. To survey the characteristics of and the effects of cognitive behavioral therapy on adolescent female suffering from the AEs in Japanese multidisciplinary pain centers.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
