Abstract
SUMMARY The effects of human growth hormone on carbohydrate and protein metabolism have been studied in monolayer tissue cultures of mouse strain L cells and human dermal fibroblasts. In strain L cell cultures, the hormone consistently caused an increase in cell number, protein synthesis, glucose consumption, and lactic acid and keto acid accumulation in the medium; in human fibroblast cultures it increased only glucose consumption and lactic acid accumulation. It affected none of these parameters in HeLa cells. Ovine growth hormone had no consistent effect on strain L cells but caused a striking increase in glucose consumption and lactic acid accumulation in the medium of human fibroblasts without changing cell number or protein synthesis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
