Abstract
The effect of glutathione monoester (GME) on buthionine sulfoximine (BSO) mediated glutathione (GSH) depletion in rats was studied to understand the defensive role of intraperitoneally supplemented GSH. Administration of glutathione mono ester (GME) (at a dose of 5 mmole/kg body weight, twice a day for 30 days) significantly prevented the buthionine sulfoximine (at a dose of 4 mmole/kg body weight, twice a day for 30 days) induced alterations. This study suggests that glutathione mono ester is hepatoprotective and plays an important role in preventing lipid peroxidation, which leads to cytotoxic effects.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
