Abstract

The article deals with the immunostimulating and immunomodeling role of germanium on the body of rats.
 The experimental animals (2 groups) were injected subcutaneously with a 0.1% solution of Germanium in liposomal emulsion at a dose of 2.0 cm3 for four consecutive days. Clinical studies were conducted according to the model of a simple clinical experiment in parallel groups of animals.
 As a result of the study, it was found that after administration of Germanium in liposomal emulsion in rats, the level of immunoglobulins of class A, M and G, respectively, increased by 43.0% (p<0.01), 70.0% (p<0.001) and 35.0% (p<0.05) compared to the control group, indicating an increase in the protective role of antibodies as a factor of humoral immunity, activation of the complement system.
 After administration of germanium in liposomal emulsion in rats, the content of circulating immune complexes increased by 20.0% (p<0.05), the content of sialic acids by 40.0% (p<0.01) and the concentration of medium weight molecules decreased by 23.0% (p<0.05) compared to the control group, which is one of the components of the immune response.

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