Abstract
In 1922, germanium dioxid was presented by Hammett, Nowrey and Mueller,<sup>1</sup>Hammett and Nowrey,<sup>2</sup>and Mueller and Iszard,<sup>3</sup>as a relatively nontoxic chemical compound with a marked erythropoietic effect on laboratory animals and of hopeful possibilities as a therapeutic agent in cases of anemia in man. As the fundamental experiments on which these conclusions were based did not appear adequate to justify the conclusions, it seemed advisable to test the drug on an animal more suited to hematologic studies than the white rat, and give more attention to evidences of increased hematopoiesis than had apparently been given by the authors mentioned. Our experiments were begun in the spring of 1922, but, owing to a variety of circumstances, have extended intermittently over a considerable period of time. In this interval, several reports have been made of the effect of germanium dioxid, not only on laboratory animals but also
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