Abstract
Backgroung: Garlic (A. sativum) is in use as a traditional medicine for millions of years. It is already establish that A. sativum is nature's best antibacterial, antiviral, antifungal, antiparasitic agent. Its helpful effects for Cardiovascular system, Blood, Immune system, Central Nervous system, Respiratory system, Anti-cancer, Anti-Inflammatory and Antidiabetic properties have already been studied. In this study, we will evaluate the effects of garlic consumption on platelets count of MI Patients along with other blood-thinning medicines. Materials & Methods: This is a cross sectional study, 500 patients were interviewed. Interview questions included demographic information, diet plan, lifestyle, garlic consumption. Results: 412 (82.45%), patients stated that they are using or have used garlic for more than 6 months in raw form to reduce the symptoms of hypertension, along with prescribed medicines such as aspirin and clopidogrel. Platelet count of all patients of the study has been monitored and results showed 22.4% of them had thrombocytopenia with less than 150,000 mcL platelet count while only 2.19% showed thrombocytosis high levels of platelets count inPatients reported symptoms of excessive fatigues, unexplained vaginal bleeding, easy bruising, extreme headache, fluctuating blood pressure and other related symptoms. Conclusion: Garlic has a really impressive and wide range of pharmacological properties including antimicrobial, anticancer, cardiovascular disease An amazing pharmacological agent like A. sativum may affect adversely if taken without precaution. High dosage of garlic results in intoxication and disturbance of platelet count. However, a careful measure should be taken before garlic consumption especially with other blood-thinning medicines.
Highlights
Garlic (A. sativum) is in use as a traditional medicine for millions of years
Platelet count of all patients of the study has been monitored and results showed 22.4% of them had thrombocytopenia with less than 150,000 mcL platelet count while only 2.19% showed thrombocytosis high levels of platelets count in complete blood count
The Rationale of our study was to evaluate the effects on platelet count, the results showed 80 (16%) patients using both prescribed medicines and garlic formula for more than 2 years with < 150,000 mcL while only 32 (6.4%) patients using just prescribed medicines without any kind of garlic formula showed the results of thrombocytopenia
Summary
Garlic (A. sativum) is in use as a traditional medicine for millions of years. We will evaluate the effects of garlic consumption on platelets count of MI Patients along with other blood-thinning medicines. Garlic has a really impressive and wide range of pharmacological properties including antimicrobial, anticancer, cardiovascular disease An amazing pharmacological agent like A. sativum may affect adversely if taken without precaution. Garlic (A. sativum) has been used as a daily diet of Egyptians [1] and as a traditional medicine for hundreds of years, [2]. In the last few decades, garlic has been studied for its immense beneficial properties of treating cardiovascular diseases [7], diabetes [8], anti-cancer [3] anti-aging effects [9]. The active compounds commonly found in garlic are Alliin, Allicin, Diallyl sulfide, Diallyl disulfide, Diallyl trisulfide, EAjoene, Z-Ajeone, S-allyl cysteine (SAC) and Thiacremonone[12] Fig 1
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