Abstract
The effect of Gardnerella vaginalis (GV) on infertility and pregnancy of albino rats were studied. Forty male and female rats were inoculated intra-vaginally with 0.02ml of GV containing 10CFU/mL. Twenty infected females were mated with infected and noninfected male rats respectively in separate large cages for a period of one month. Also, ten gravid rats were similarly inoculated and observed till delivery. The result of the study indicated a 20-40% reduction in impregnation and 70-80% decrease in the number of offsprings produced among the infected rats. Also, the survival rates of the offsprings after 7 days reduced drastically among the infected rats. There were cases of abortion and delivery of feeble/underweight rats among the infected pregnant rats. This study shows that GV could be a factor worthy of consideration in the cases of infertility and pregnancy associated complications in rats. Further investigation is recommended to determine the effect of this organism on infertility and pregnancy complications in human subjects.
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