Abstract
The organization as well as the positive staining pattern of mouse skin collagen fibrils treated with 500 rad gamma irradiation were studied by electron microscopy. The parallel packing of fibrils remained throughout without any areas of disorganization, also all fibrils were seen to retain normal banding periodicity. These observations suggest that gamma irradiation leads to aggregation of collagen into a regular arrangement of fibrils, as well as to normal axial relationships between the molecules within a fibril.
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