The Effect of Ferritin, Vitamin D, and Some Hormonal and Biochemical Parameters on Patients with Female-pattern Hair Loss after COVID-19 Infection

Abstract

BACKGROUND: This study aims to shed light on the problem of female-pattern hair loss, especially for women, after recovering from the viral infection of COVID-19 and their deficiency of iron store level, Vitamin D, and some parameters that cause complications. MATERIALS AND METHODS: The study included Sixty-eight females ranging from 20 to 30 years old; they were divided into two groups. Group I has 18 women as a control group; the women had recovered from COVID-19 infection and were not affected by viral complications. Group II of 50 women had recovered from infection with COVID-19 and suffered from hair loss. Levels of iron stores (ferritin), Vitamin D3, thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone, testosterone hormone, triglycerides (TGs), and serum total cholesterol (TC) were measured after 2 months of infection recovery and compared with controls. RESULTS: The results of TG showed a significant increase (P ≤ 0.05) between women in Group II compared to the control group (Group I). On the other hand, the data obtained from both Vitamin D3 and ferritin levels showed a significant decreases (P ≥ 0.001 in Group II compared to the control group (Group I). In contrast, there is no statistical significance recorded in hormonal parameters, except testosterone hormone, which witnessed a highly significant increase (P ≤ 0.01) of Group II, whereas for TC, there was no statistical significance. In addition, a high positivity was also observed (P < 0.01, P = 0.05) for ferritin, Vitamin D, testosterone, and TG level in the blood. CONCLUSIONS: Our results showed a close co -relation between low levels of Vitamin D3, ferritin, high male hormones, and hair loss complications with COVID-19 viral infection. Both ingredients are consumed to protect the body from viruses. Vitamin D plays a major role in stimulating the body’s immunity to disease, so their concentration decreases after recovery from the disease and after the appearance of symptoms of the effects that have occurred because of this deficiency.