Abstract
Eight healthy men (17–31 yr) were studied in the postabsorptive state(control) and after a 59-h fast. They had venous blood drawn at rest and during 10 min of moderate work (treadmill running requiring 60% of the individual maximal oxygen uptake) succeeded by 5 min of heavy work (requiring 100% of the individual maximal oxygen uptake). Fasting resulted in a halving of insulin concentrations, a slight reduction in glucose concentrations, and ketonuria. Comparing levels during heavy work between 59–h–fasted and postabsorptive subjects, the concentrations of norepinephrine [36.5 ± 3.7 us.19.5± 2.5 nmol liter−1 (mean and SE)], epinephrine (6.8 ± 2.1 us.2.0 ± 0.4 nmol liter−1),glucagon (18.9 ± 2.9 us. 7.5 ± 0.7 pmol liter−1), GH (77 ±11 us.34 ± 14 µU ml−1), cortisol (491 ± 97 us. 34 ± 44 nmol liter−1), PRL (19 ± 5 us. 11 ± 2 µg liter−1), FFA, glycerol, and lactate were higher after fasting than in control experiments. The concentration of vasoactive intestinal polypeptide was higher at rest, but not significan...
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