Abstract
The effect of exposure to long working hours on ischaemic heart disease: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury
Highlights
Introduction backgroundThe World Health Organization (WHO) and the International Labour Organization (ILO) are finalizing Joint Estimates of the workrelated burden of disease and injury (WHO/ILO Joint Estimates) (Ryder, 2017)
We present a systematic review and metaanalysis of parameters for estimating the number of deaths and disability-adjusted life years from ischaemic heart disease (IHD) that are attributable to exposure to long working hours, for the development of the WHO/ILO Joint Estimates
We found that compared with working 35–40 h/week, working 49–54 h/week there was an elevated risk with lower confidence bound below 1 of dying from IHD (RR 1.01, 95% CI 0.82 to 1.25, 11 studies, 284,474 participants, I2 13%; Fig. 12)
Summary
Introduction backgroundThe World Health Organization (WHO) and the International Labour Organization (ILO) are finalizing Joint Estimates of the workrelated burden of disease and injury (WHO/ILO Joint Estimates) (Ryder, 2017). The WHO/ILO Joint Estimates are based on already existing WHO and ILO methodologies for estimating the burden of disease for selected occupational risk factors (Ezzati et al, 2004; International Labour Organization, 1999; 2014; Pruss-Ustun et al, 2017). They expand these existing methodologies with estimation of the burden of several prioritized additional pairs of occupational risk factors and health outcomes. We present a systematic review and metaanalysis of parameters for estimating the number of deaths and disability-adjusted life years from IHD that are attributable to exposure to long working hours, for the development of the WHO/ILO Joint Estimates. For the bodies of evidence for both outcomes with any eligible studies (i.e. IHD incidence and mortality), we did not have serious concerns for risk of bias (at least for the cohort studies)
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