Abstract

Summary. 1 The effect on the urinary excretion of adrenaline and nor-adrenaline of moderate amounts of alcohol which gave peak blood levels of 0.015–0.080 per cent was studied in healthy human subjects. 2 The urinary adrenaline excretion was found to increase significantly in the alcohol experiments when compared to control experiments. The increase was already noticeable when the peak blood alcohol concentration was below 0.04 per cent. No consistent change in the urinary noradrenaline excretion was observed after alcohol intake. 3 It is concluded that the increased adrenaline excretion is due to adrenal medullary stimulation. Some possible mechanisms for this effect are discussed.

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