The effect of elevated metabolism on rate of intestinal contractions

Abstract

1. Thyroid extract, in doses sufficient to elevate metabolism fifty per cent, does not alter the rate of contraction in exteriorized intestinal loops in dogs (Fig. 1) except in a segment just above the ileocecal valve (Fig. 2). 2. Alpha 1, 2, 4 dinitrophenol, in doses sufficient to elevate metabolism over 200–500% does not increase the rate of contraction (Fig. 3) in exteriorized intestinal loops in dogs. 3. Feeding reactions are poor with both these drugs.