Abstract

Aim: to investigate the effect of early enteral nutrition (EEN) on immune function and inflammatory reaction in patients with severe acute pancreatitis (SPA). Methods: 70 patients with SPA were randomly divided into EEN group and DEN group (delayed enteral nutrition). On the basis of routine treatment, EEN group was treated with enteral nutrition support within 72 hours after onset, and DEN group was given enteral nutrition support therapy on the 5th day after onset, and the course of treatment was 2 weeks. The immune indexes, inflammatory cytokines and clinical symptoms were compared between the two groups before and after treatment.Results: after treatment, CD3 cells, CD4, CD4 / CD8 cells, NK cells, B lymphocytes and IgA, IgG, IgM (immunoglobulin) were increased in both groups (P

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