Abstract

Objective: The purpose of this study was to evaluate the effects of a simple dietary intervention for individuals with chronic spinal cord injury(SCI)and moderately elevated total cholesterol.Methods: Baseline and follow–up serum lipid values were obtained on 222 persons with SCI. Eighty–six individuals with total cholesterol>200mg∕dL were referred for dietary consultation (group 1). The remainder with values <200 mg∕dL and no consultation served as controls(group 2).Results: At average follow–up of 16 months, group 1 demonstrated significant declines in total cholesterol and low–density lipoproteincholesterol (LdL–C), whereas group 2 demonstrated significant increases in total cholesterol. Triglyceride levels followed similar butnonsignificant patterns. There were no significant changes in high–density lipoprotein cholesterol for either group. In group 1,17’7’o had clinically significant reductions in total cholesterol to <200 mg∕dL and 21 ’7’o had reductions of LdL–C from >135 mg∕dL to <135 mg∕dl.Conclusions: Dietary intervention should be an initial treatment for those with SCI and moderately elevated total cholesterol, with the expectation that approximately 20% will respond favorably.

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